Pharmaceutical Industries Research division

Division name: Pharmaceutical and Drug Industries Research Division.

Vision: The Pharmaceutical and Pharmaceutical Industries Research Division should be an expert house and a bank for scientific consultations for the development of pharmaceutical and drug research in the Arab Republic of Egypt, the Arab world and Africa.

Mission: Providing services and scientific consultations to solve the problems of the pharmaceutical industry based on the application of comprehensive quality standards, through well trained scientific staff that lead the applied research to develop the pharmaceutical and drug fields with effective participation in the service of society and pushing the production sectors to local, regional and global competition.

Objectives:

1- National pharmaceutical industry and identify the challenges of this industry.

2- Researches and research projects in the applied multidisciplinary approach to serve the pharmaceutical industry and determine the quality standards of these researches.

3- Excellent research and management competencies with the provision of the appropriate environment for that.

Departments:

1- Chemistry of Medicinal Plants Department: It aims to develop the ways of separating and identifying the effective chemical ingredients from medicinal plants, introduce new environmental green technology in the field of extracting of medicinal plants and the comprehensive screen of Egyptian medicinal plants.

 

2-Phytochemistry and Plant Systematics Department: The work in this department is focused on the identification and documentation of many Egyptian plants, especially the wild ones which are presented in Sinai, Nile Valley and North coast. In addition, it concerns with the modernization of the reference herbarium with all plant groups in Egyptian flora to be covered by all species, especially wild ones.

 

3-Chemistery of Natural Compounds Department: The department aims to isolate, purify and identify the different natural compounds with biological efficacy from their natural sources and conduct chemical modifications on the biologically active compounds to increase or modify their biological activity.

 

4- Chemistry of natural and microbial products Department: The mission of this section is to explore new drugs from microbial and chemical sources by using modern technologies, cooperation with the pharmaceutical industry to manufacture local pharmaceutical raw materials, introduction of new technologies in the field of microbial fermentation and the production of enzymes for industrial applications.

 

5- Pharmacognosy Department: The department concerns with basic and semi-applied researches in the field of the drug discovery from natural sources. It is also concern with constants and synthetic standards of natural products, DNA sequence technology to confirm DNA fingerprint and plant tissue culture technology to improve the production of materials with therapeutic value.

 

6- Therapeutic Chemistry Department: The Department conducts researches in health and environment through the field of therapeutic chemistry and biology. The department concerns with studying the chemical construction of new pharmaceutical compounds, developing and improving the efficiency of medicines and developing new treatment for infectious, endemic and chronic diseases from natural sources of plants or animals.

7- Medicinal and Pharmaceutical Chemistry Department: The objectives of this department are to design, synthesis, molecular modeling, pharmacological evaluation of new chemical candidates  and formulation of modified release oral dosage forms of selected drugs.

8- Pharmaceutical Technology Department: This section is concerned with studying all aspects related to the formulation of various pharmaceutical materials in effective and safe pharmaceutical form.

 

9- Medicinal and Aromatic Plants Research Department: This section directs its activity towards the production of medicinal and aromatic plants of distinct economic importance in Egypt, especially the newly reclaimed land and communication to the technological packages that serve the production of medicinal and aromatic plants.

Special Units:

1- Special Unit for Analysis and Evaluation of Essential Oils and Concretes The Unit aims to assist producers, exporters and research students in the field of essential oils and concretes to obtain basic information about essential oils and concretes, for the purpose of proper evaluation of the product and the appropriate conditions for storing and handling it and ensuring that it fulfills the standardization required for each product.

The main activities of the unit are:

  • Extraction of the volatile oils and determination its percentage from its different sources, as well as studying the physical and chemical properties of these oils.
  • Extraction and determination the proportion of aromatic concretes from aromatic plants, and study their physical properties.
  • Identification of different chemical compounds of essential oil using special devices, most notably the GC-MS and its relative percentages in the oil.
  • Matching the specifications of essential oils to the standard specifications for each oil in the references.
  • Provide advice and consultation on the best conditions for the storage and  handling each oil.
  • Preparation the extracts of medicinal and aromatic plants with different organic solvents, and evaluate them.

 

2- Special Unit of the pressing and extraction of natural oils

  • Natural oils are divided into fixed oils such as almond oil, jojoba oil, watercress oil, castor oil, pumpkin oil and volatile oils such as mint oil, marjoram oil, basil oil and chamomile oil.
  • The unit aims to provide these oils and other herbal extracts to researchers in the National Center for Research and other Research Centers and various Universities, especially researchers in the field of veterinary medicine, plant diseases and plant protection and microbiology.
  • In addition to providing these centers with pure oils for human consumption and poultry farms and animal production. The unit also provides advice and guidance to the users of these oils.

3- Special Unit of Pharmacognosy and Chemistry of Medicinal Plants

Main objectives:

  • Pharmacognostical Analysis of Medicinal Plants
  • Standardization of Medicinal Plants According to the Pharmacopoeal Constants.
  • Examination and Analysis of Crude Drugs:

– Determination of Pharmacopoeal Constants

– Determination of Foreign Organic Matter

– Determination of Volatile Substances

– Extraction of Drugs & Determination and Identi-fication of Biologically Active Constituents.

  • Carrying out Analytical Services, Giving Consultations and Holding Courses in all the above Mentioned Activities.

3- Special Unit of Pharmacognosy and Chemistry of Medicinal Plants

Main objectives:

  • Pharmacognostical Analysis of Medicinal Plants
  • Standardization of Medicinal Plants According to the Pharmacopoeal Constants.
  • Examination and Analysis of Crude Drugs:

– Determination of Pharmacopoeal Constants

– Determination of Foreign Organic Matter

– Determination of Volatile Substances

– Extraction of Drugs & Determination and Identi-fication of Biologically Active Constituents.

  • Carrying out Analytical Services, Giving Consultations and Holding Courses in all the above Mentioned Activities.

 

5- Special Unit of Domestic Chemicals

  • The unit includes the production activities and services
  • – Production activities include white vinegar and cosmetics such as shampoo balsam and shower gel
  • Services include chemical and biological analysis of the industrial Samples eg cane and beet molasses.

 

6- Special Unit of Bioassay–Cell Culture Unit

  • In vitro bioassays on human tumor cell lines for drug discovery laboratory has been established in National Research Centre, Pharmacognosy department since 1999 to serve the anticancer drug discovery.
  • The laboratory is fully specialized with the needed equipment according to international standards and has about 26 human cancer cell lines beside 3 normal cell lines and two cancer animal models one for colon cancer by using C26 cell line and other breast cancer model by using 4T1 cell line.
  • The laboratory tests about 1000 samples for anticancer activity per year given by different research groups from universities and research institutes around Egypt.

7- Special Unit of Metabolomics 

  • Metabolomic analysis of plants and animals specimens.
  • * Under construction.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

x

Check Also

Oral

Oral & Dental Research division

Division name: The Oral Dental Research Division Vision: The division represents a scientific center of excellence through undertaking basic and ...